On May 22, 1883, the St. Louis Browns knocked off the Columbus Buckeyes 6-3 at Sportsman's Park. The club who would later become known as the Cardinals, saw their first baseman Charlie Comiskey score one of the runs without the benefit of a hit. The scoring play started when Comiskey was called out on a third strike, but the ball got past the Columbus catcher Rudy Kemmler, and Comiskey dashed all the way to second base before he could round it up. Moments later, the Buckeyes hurler Frank Mountain delivered another wild pitch that brought Comiskey flyin around to score.
Comiskey is best known as the longtime owner of the Chicago White Sox. However, his playing days as a professional began in St. Louis when he was just 22 years old with the upstart Browns of the American Association. By the end of the 1883 season, Comiskey was named the player/manager of the St. Louis club. The team won four straight American Association Pennants with Comiskey at the helm, and in 1886 guided the club to its first World Championship title, by knocking off the Chicago White Stockings in six games (The club also laid claim to the title in 1885. However, it was disputed and the Series was called a draw).
You can read more about the life and times of Charlie Comiskey here: