On May 28, 1950, at Crosley Field in Cincinnati, Ohio, Joe Garagiola started the second game of a doubleheader against the Reds with a bang. The Cardinals catcher cleared'em all with a Grand Slam off Ewell Blackwell, at that point the Reds Manager Luke Sewell had seen enough and yanked his starter in the first inning. The Cards would cruise to a 7-2 win to cap off a perfect day, they won the first contest 6-2.
Check out the box scores
Game 1: http://www.baseball-reference.com/boxes/CIN/CIN195005281.shtml
Game 2: http://www.baseball-reference.com/boxes/CIN/CIN195005282.shtml